A rare situation where only one of the two copies of a particular tumor-suppressor gene needs to be inactivated before there is a progression toward cancer is called:
A: haploinsufficiency.
B: clonal evolution.
C: loss of heterozygosity.
D: signal transduction.
E: aneuploidy.
A: haploinsufficiency.
B: clonal evolution.
C: loss of heterozygosity.
D: signal transduction.
E: aneuploidy.
举一反三
- 中国大学MOOC: A rare situation where only one of the two copies of a particular tumor-suppressor gene needs to be inactivated before there is a progression toward cancer is called:
- Which of the following statements is right? A: RB exerts anti-proliferative effects by controlling the G1-to-S transition of the cell cycle B: RB is a key positive regulator of the cell cycle C: The TP53 was the first tumor suppressor gene to be discovered by the study of retinoblastoma D: Malignant transformation is only derived from one of the normal RB alleles inactivated
- Tumor suppressor genes encode proteins that normally restrain cell division. Mutation in one or more of these genes can lead to tumor formation.
- A________ trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. A: determinant B: dormitory C: dominant D: dormant
- In about 150 Ma before recent there was only one continent called Pangea,and one ocean called Panthalassa.