The enzyme that catalyzes the condensation of acetyl-CoA with oxaloacetate is _______ _.
举一反三
- The α-ketoglutarate dehydrogenase complex closely resembles the large enzyme complex that converts pyruvate to acetyl CoA, the pyruvate dehydrogenase complex.
- The conversion of pyruvate to Acetyl CoA is the rate limiting step acetyl CoA synthesis.（）
- E2 (dihydrolipoamide acetyltransferase or dihydrolipoyl transacetylase, DLAT) of the pyruvate dehydrogenase complex catalyzes a __________________ in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group.
- Amplification results when an enzyme associated with a signal receptor is activated and, in turn, catalyzes the activation of many molecules of a second enzyme, each of which activates many molecules of a third enzyme, and so on, in a so-called _____________________.
- The first step in the formation of acetoacetate in liver mitochondrial matrix, is the enzymatic condensation of two molecules of acetyl-CoA to form acetoacetyl-CoA by __________. Acetoacetyl-CoA then condenses with acetyl-CoA by HMG-CoA synthaseto form β-hydroxy-β-methylglutaryl-CoA (HMG-CoA), which is cleaved to free acetoacetate and acetyl-CoA by ______________.