If ER soluble proteins with the KDEL sequence at the C-terminus, escaped to Golgi apparatus, their corresponding receptor in COPII-coated vesicles acts mainly to retrieve the proteins back to ER through vesicle transport.
举一反三
- Short regions of α helix are especially abundant in proteins that are embedded in cell __________, such as transport proteins and receptors.
- KDEL序列是ER可溶性蛋白的驻留信号,因此识别KDEL的受体只分布在ER膜上。
- The first step in the secretory pathway, from the ER to Golgi, is mediated by ( ).
- Some nuclear receptor proteins may be activated by intracellular metabolites rather than by secreted signal molecules.
- The method that can be used to sequence the proteins is A: MS B: X-ray cystallography C: NMR D: Cyro-EM