A: incomplete absorption
B: first pass effect
C: both
D: neither
举一反三
- Which of the following types of<br/>the administration route may appear first pass elimination? () A: intramuscular<br/>injection B: inhalation<br/>administration C: sublingual<br/>administration D: oral<br/>administration E: subcutaneous<br/>injection
- Which<br/>of the following routes of administration has the highest<br/>bioavailability?() A: Intramuscular B: Intravascular C: Oral D: Subcutaneous E: Sublingual
- Which of the following routes of administration can achieve the highest bioavailability?() A: Oral B: Intravenous injection C: Intramuscular injection D: Inhalation E: Sublingual
- Which route of administration can have a higher bioavailability than oral route?
- The<br/>bioavailability is() A: the<br/>quantity of drug absorbed after oral administration B: the<br/>rate of drug absorbed after oral administration C: the<br/>ratio of AUC(oral)/AUC(intravenous) D: the<br/>ratio of AUC (intravenous)/AUC(oral) E: the<br/>area under curve of oral administration
内容
- 0
Bioavailability of drugs is A: established by FDA regulation at 100% for preparations for intramuscular injection B: 100% for oral preparations that are not metabolized in the liver C: calculated from the peak concentration of drug divided by the dose administered D: important because bioavailability determines what fraction of the administered dose reaches the systemic circulation E: equal to 1 (100%) only for drugs administered by any parenteral route
- 1
首过效应的英文是:() A: head pass effect B: head past effect C: first pass effect D: first past effect
- 2
Which route of administration is MOST likely to subject a drug to a first-pass effect? A: IV B: Inhalational C: Oral D: Sublingual E: IM
- 3
The first-pass effect occurs most often after which route of drug administration: A: Sublingual B: Intravenous C: Oral D: Subcutaneous E: Inhalation
- 4
The bioavailability of L-dopa is very low, this is due to A: difficulty to pass through the brain barrier B: rapid acetylation in liver C: peripheral hydroxylation D: a low absorption rate E: rapid peripheral decarboxylation