Normally, if a healthy cell acquires too many mutations to develop properly, the p53 gene will initiate cellular suicide. If this gene stops working, however, the cell keeps growing and can become malignant .
举一反三
- Which of the following is correct about pro-oncogene? A: It is a normal cellular gene B: They are normally involved in the control of the cell cycle C: When mutated or inappropriately expressed,can cause a cell to become malignant D: All of the above
- What will happen if the p53 gene stops "working"?
- When you doing transgenic plant, you could do overexpression, gene knock-down or gene knock out. Overexpression usually refers to an experiment when DNA is added to the cell to force expression of the gene to a much higher than normal level.（）
- Which of the following statements is right? A: RB exerts anti-proliferative effects by controlling the G1-to-S transition of the cell cycle B: RB is a key positive regulator of the cell cycle C: The TP53 was the first tumor suppressor gene to be discovered by the study of retinoblastoma D: Malignant transformation is only derived from one of the normal RB alleles inactivated
- Which gene transfer technique involves a tiny needle which is used to inject DNA into a cell lacking that DNA sequence