Protein folding has been studied in the laboratory using highly purified proteins. A protein can be unfolded, or denatured, by treatment with _______ that disrupt the noncovalent interactions holding the folded chain together.
举一反三
- The exact 3D structure of a purified protein can be determined by __________ and ____________.
- Covalent modifications added to a protein’s amino acid side chains can control the location and function of the protein and can serve as docking sites for other proteins.
- A part of protein sequence that can form a compact three-dimensional structure and often can be independently folded is called ______.
- Highly efficient protein machines are formed by assemblies of allosteric proteins in which the various conformational changes are coordinated to perform complex functions.
- Many proteins can be grouped into protein families, in which each family member has an amino acid sequence and a three-dimensional conformation that closely ________ those of the other family members.