It is apparently that ignorance of humans cause their own afflictions. A: It is apparently that ignorance of humans causes their own afflictions. B: It is apparent that ignorance of humans causes their own afflictions . C: It is apparent that ignorance of humans has caused their own afflictions. D: It is apparent that ignorance of humans have caused their own afflictions.

When Chris was not able to pick up his son from the kindergarten, he was in great _____（痛苦）all night long. He suffered deep afflictions.