Which route of administration is MOST likely to subject a drug to a first-pass effect? A: IV B: Inhalational C: Oral D: Sublingual E: IM

All of the following are<br/>inhalational agents, which agents its MAC value is 1.77? () A: Sevoflurane B: Enflurane C: Halothane D: Isoflurane E: Nitrous oxide