The most relevant measurement in single dose bioavailability studies is
A: maximum drug serum concentration
B: time to maximum serum concentration
C: area under serum concentration –time curve (AUC)
D: time for peak drug concentration to fall to half
E: time to appearance of drug in circulation (lag time)
A: maximum drug serum concentration
B: time to maximum serum concentration
C: area under serum concentration –time curve (AUC)
D: time for peak drug concentration to fall to half
E: time to appearance of drug in circulation (lag time)
举一反三
- In<br/>terms of bioavailability, the following statements are true() A: The<br/>amount of a drug absorbed into the bloodstream B: The<br/>total amount of drug in the body at peak concentration C: The<br/>total amount of drug in the body at a steady-state concentration D: The<br/>amount and rate at which a drug is absorbed into the systemic<br/>circulation E: The<br/>amount of drug that passes through the gastrointestinal tract into<br/>the hepatic portal vein
- Before administering a medication, the nurse must verify the rights of medication administration, which include: A: right patient, right bed, right drug, right route, right dose, and right time. B: right drug, right dose, right route, right time, right physician, and right documentation. C: right patient, right drug, right route, right time, right documentation, and right equipment. D: right patient, right drug, right dose, right concentration, right route, right time, and expiration date.
- Km is defined as A: Substrate concentration at maximum velocity B: Substrate concentration at half the maximum velocity C: Enzyme concentration D: Optimum temperature
- Half-life is the time for the concentration of a reactant decreases by half.
- Bioavailability is: A: Amount of drug that reach the systemic circulation B: Drug metabolized in liver before the drug reaches the systemic circulation C: Drug metabolized in liver after the drug reaches the systemic circulation D: Maximum by rectal route