A: maximum drug serum concentration
B: time to maximum serum concentration
C: area under serum concentration –time curve (AUC)
D: time for peak drug concentration to fall to half
E: time to appearance of drug in circulation (lag time)
举一反三
- In<br/>terms of bioavailability, the following statements are true() A: The<br/>amount of a drug absorbed into the bloodstream B: The<br/>total amount of drug in the body at peak concentration C: The<br/>total amount of drug in the body at a steady-state concentration D: The<br/>amount and rate at which a drug is absorbed into the systemic<br/>circulation E: The<br/>amount of drug that passes through the gastrointestinal tract into<br/>the hepatic portal vein
- Before administering a medication, the nurse must verify the rights of medication administration, which include: A: right patient, right bed, right drug, right route, right dose, and right time. B: right drug, right dose, right route, right time, right physician, and right documentation. C: right patient, right drug, right route, right time, right documentation, and right equipment. D: right patient, right drug, right dose, right concentration, right route, right time, and expiration date.
- Km is defined as A: Substrate concentration at maximum velocity B: Substrate concentration at half the maximum velocity C: Enzyme concentration D: Optimum temperature
- Half-life is the time for the concentration of a reactant decreases by half.
- Bioavailability is: A: Amount of drug that reach the systemic circulation B: Drug metabolized in liver before the drug reaches the systemic circulation C: Drug metabolized in liver after the drug reaches the systemic circulation D: Maximum by rectal route
内容
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What’s more, I could write ____. A: full time B: as a secondary occupation C: with more concentration D: with enough time
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Bioavailability of drugs is A: established by FDA regulation at 100% for preparations for intramuscular injection B: 100% for oral preparations that are not metabolized in the liver C: calculated from the peak concentration of drug divided by the dose administered D: important because bioavailability determines what fraction of the administered dose reaches the systemic circulation E: equal to 1 (100%) only for drugs administered by any parenteral route
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Efficacy means A: the concentration at which the drug elicits 50% of its maximal effect B: the maximal effect produced by the drug C: the dose at which 50% of subjects exhibit a therapeutic response to a drug D: the dose at which 50% of subjects dies E: the dose at which 50% of subjects exhibit a toxic reaction
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The amount of time you can concentrate on something is called your concentration ____. A: width B: span C: depth D: involvement
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In the study of pharmacokinetics and bioavailability, LLOQ should be able to determine the drug concentration in biosamples at 3-5 elimination half-lives after dosing or within the range of 1/5 to 1/2 of the Cmax.