Bioavailability is:
A: Amount of drug that reach the systemic circulation
B: Drug metabolized in liver before the drug reaches the systemic circulation
C: Drug metabolized in liver after the drug reaches the systemic circulation
D: Maximum by rectal route
A: Amount of drug that reach the systemic circulation
B: Drug metabolized in liver before the drug reaches the systemic circulation
C: Drug metabolized in liver after the drug reaches the systemic circulation
D: Maximum by rectal route
举一反三
- Bioavailability reflects that A: The size of apparent distribution volume B: Amount of drug entering systemic circulation C: The length of half-life of drug plasma D: Effect of drug absorption rate on drug efficacy E: The speed of drug elimination
- Bioavailability of drugs is A: established by FDA regulation at 100% for preparations for intramuscular injection B: 100% for oral preparations that are not metabolized in the liver C: calculated from the peak concentration of drug divided by the dose administered D: important because bioavailability determines what fraction of the administered dose reaches the systemic circulation E: equal to 1 (100%) only for drugs administered by any parenteral route
- In<br/>terms of bioavailability, the following statements are true() A: The<br/>amount of a drug absorbed into the bloodstream B: The<br/>total amount of drug in the body at peak concentration C: The<br/>total amount of drug in the body at a steady-state concentration D: The<br/>amount and rate at which a drug is absorbed into the systemic<br/>circulation E: The<br/>amount of drug that passes through the gastrointestinal tract into<br/>the hepatic portal vein
- Absorption is the process of a drug entering systemic circulation from its site of administration. 这里administration的意思是？
- Absorption is the movement of a drug from the site of administration to the A: gastrointestinal tract B: systemic circulation C: portal vein D: cell E: action site