In the study of pharmacokinetics and bioavailability, LLOQ should be able to determine the drug concentration in biosamples at 3-5 elimination half-lives after dosing or within the range of 1/5 to 1/2 of the Cmax.
举一反三
- The most relevant measurement in single dose bioavailability studies is A: maximum drug serum concentration B: time to maximum serum concentration C: area under serum concentration –time curve (AUC) D: time for peak drug concentration to fall to half E: time to appearance of drug in circulation (lag time)
- If a drug with t1/2 3 hours is given intravenously, the blood concentration will drop below 5% of the initial concentration within: A: 6 h B: 9 h C: 15 h D: 25 h E: 30 h
- range(5)表示的范围是_________。 A: [0, 1, 2, 3] B: [1, 2, 3, 4] C: [0, 1, 2, 3, 4] D: [1, 2, 3, 4, 5]
- 语句 for i in range(5) 中，每次循环时i的值为多少？ A: 0 1 2 3 4 B: 1 2 3 4 5 C: 0 1 2 3 4 5 D: 1 2 3 4
- 一个待排序的数据元素序列为{5, 4, 3, 2, 1}，采用基本插入排序对其进行排序，以下（ ）是插入排序每一趟的结果。 A: 4 5 3 2 1 3 4 5 2 1 2 3 4 5 1 1 2 3 4 5 B: 5 4 3 1 2 5 4 1 2 3 5 1 2 3 4 1 2 3 4 5 C: 4 3 2 1 5 3 2 1 5 4 2 1 5 4 3 1 5 4 3 2 D: 4 5 3 2 1 2 3 4 5 1 3 4 5 2 1 1 2 3 4 5