The adverse reactions of fluoroquinolones including the following EXCEPT: A: Tendinitis and tendon rupture B: Effects on bony structure and teeth C: Allergic effect: skin rash, phototoxicity D: Cardiac arrhythmias: QT interval prolongation E: Hepatotoxicity and nephrotoxicity

Which one of the following statements is false? A: Imipenem is often used with cilastatin which can inhibit renal tubular dehydropeptidase Ⅰ in clinic B: First-generation Cephalosporins have higher resistance to beta-lactamases and no nephrotoxicity C: Do not mix aminoglycosides with beta-lactam antibiotics in the same infusion bottle D: Third-generation Cephalosporins have enhanced activity against G- bacteria E: Streptomycin is effective against mycobacterium tuberculosis