A 35-year-old man with severe hypercholesterolemia has a family history of deaths at a young age from heart disease and stroke. Which of the following genes is likely to be defective?
A: Apolipoprotein E
B: The LDL receptor
C: Lipoprotein lipase
D: PCSK9
E: LCAT
A: Apolipoprotein E
B: The LDL receptor
C: Lipoprotein lipase
D: PCSK9
E: LCAT
举一反三
- When you talk to a 60 year old man, he suddenly feels unwell, one arm<br/>can't move, and it's difficult to speak. What's the most likely<br/>problem with him?() A: Suffocation B: Heart disease C: Stroke D: Diabetes coma E: Shock
- Which of the following are the most common and clinically useful risk factors for the breast cancer? A: Fibrocystic disease, age and gender B: Cysts, family history in immediate relatives and gender C: Age, gender and family history in immediate relatives D: Obesity, Nulliparity and alcohol use
- 2. According to the passage, which of the following is NOT the disease caused by stress? A: Heart attack. B: Stroke. C: Ulcer. D: Lung infection.
- A 35-year-old man is awakened at night because of severe lower abdominal pain that radiates to the groin. The pain is very intense and comes in waves. The next morning， he notices blood in his urine. On examination， there are no remarkable findings. Which of the following is the most likely diagnosis？（ ） A: Acute cystitis B: Renal cell carcinoma C: Ureteral lithiasis D: Hydronephrosis E: Autosomal dominant polycystic kidney disease
- The individuals who have mutations in the LDL receptor that prevent the normal uptake of LDL by liver and peripheral tissues, would result in ( ) A: Lesch-Nyhan<br/>syndrome B: Familial hypercholesterolemia C: Niemann-Pick Type C disease D: Atherosclerosis