• 2021-04-14
    Directions:TranslateintoEnglishtheChinesesentencesgiveninthebracketstocompletetheabstract.


    AbstractThep8geneisarecentlyidentifiedgenewithmitogenicactivity._______________________(在急性胰腺炎pancreatitis、胰腺发育pancreaticdevelopment及再生regeneration中均可诱导表达。)However,theexpressionofp8inpancreaticcancerisnotreported._______________________(本项研究旨在通过免疫组化研究包括38例胰腺癌在内的72例人胰腺组织中的p8基因表达。)__________________________(38例胰腺癌中有27例(71%)p8基因过度表达(在1,000个细胞中阳性细胞>25%),而慢性胰腺炎中仅有17%。)Therewasnooverexpressioninmucinouscystadenomaorinnormalpancreas._______________________(与其他病例相比胰腺癌中p8基因过度表达明显增高(p<0.05)。)Reversetranscription-PCRanalysisconfirmedp8mRNAoverexpression(tumor/nontumorratio>2)in75%(3of4)0fPCs.Thep8wasover-expressedalsoinhumanpancreaticcancerlines(MIAPaCa-2andPANC-1)._______________________(研究结果表明p8基因参与了胰腺癌的发生,反应出其有丝分裂活动。)